Name: Human RELT/TNFRSF19L Recombinant Protein (Fc Tag)

Synonyms: Tumor necrosis factor receptor superfamily member 19L;TNFRSF19L;Receptor expressed in lymphoid tissues;RELT

Expression host: HEK293 Cells

Sequence: Ser26-Ala160

Accesstion: Q969Z4

Species: Human

Mol_Mass: 41.4 kDa

AP_Mol_Mass: 40-60 kDa

Tag: C-Fc

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin:

Storage: Store at

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at

Formulation: Supplied as a 0.2 μm filtered solution of PBS, pH7.4.

Reconstitution: Not Applicable

Background: Tumor necrosis factor receptor superfamily member 19L (TNFRSF19L), also known as Receptor expressed in lymphoid tissues and RELT, is a member of the TNF-receptor superfamily. TNFRSF19L is a single-pass type membrane protein and contains one TNFR-Cys repeat. TNFRSF19L is highly expressed in spleen, lymph node, thymus, peripheral blood leukocytes, bone marrow and fetal liver. It has been shown TNFRSF19L activates the NF-kappaB pathway and selectively binds TNF receptor-associated factor 1 (TRAF1). TNFRSF19L is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response.

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