Name: Human PSPH Recombinant Protein (His Tag)

Synonyms: Phosphoserine Phosphatase;PSP;PSPase;L-3-Phosphoserine Phosphatase;O-Phosphoserine Phosphohydrolase;PSPH

Expression host: E.coli

Sequence: Met 1-Glu225

Accesstion: P78330

Species: Human

Mol_Mass: 26.1 kDa

AP_Mol_Mass: 25-30 kDa

Tag: C-His

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin:

Storage: Store at

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 4M Urea, 5mM EDTA, pH 8.0.

Reconstitution: Not Applicable

Background: Phosphoserine Phosphatase (PSP) is an enzyme that belongs to the serB family. PSPH catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates. Deficiency of this protein is thought to be linked to Williams syndrome. A disorder that results in pre- and postnatal growth retardation; moderate psychomotor retardation and facial features suggestive of Williams syndrome.

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