Name: Human PSA/KLK3 Recombinant Protein (aa 25-261, His Tag)
Synonyms: APS;Hk3;KLK2A1;PSA;Prostate-Specific Antigen;PSA;Gamma-Seminoprotein;Seminin;Kallikrein-3;P-30 Antigen;Semenogelase;
Expression host: HEK293 Cells
Sequence: Ile25-Pro261
Accesstion: P07288
Species: Human
Mol_Mass: 27.1 kDa
AP_Mol_Mass: 35 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, 10mM CaCl2, 150mM NaCl, 0.05% Brij 35, pH 7.5.
Reconstitution: Not Applicable
Background: KLK3; also known as APS; is short for Prostate-specific antigen. It is a 261 aa. protein which belongs to the peptidase S1 family and Kallikrein subfamily. This protein has 5 isforms produced by alternative splicing. It is a secreted protein and can forms a heterodimer with SERPINA5 which can inhibit its activity. KLK3 is also strongly inhibited by Zn2+; 100 times more abundant in semen than in serum. This inhibition is relieved by exposure to semenogelins; which are avid zinc binders. KLK3 can hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
LIGHT/TNFSF14 Protein
Animal-Free FGF-21 Protein
Popular categories:
4-1BBL/CD137L
Gastric Inhibitory Peptide (GIP)