Name: Human Prolactin/PRL Recombinant Protein
Synonyms: Prolactin;PRL
Expression host: E.coli
Sequence: Leu29-Cys227
Accesstion: P01236
Species: Human
Mol_Mass: 23 kDa
AP_Mol_Mass: 25 kDa
Tag: None
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM Nacl, 1mM EDTA, pH 7.4.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the p
Reconstitution: Please refer to the printed manual for detailed information.
Background: Prolactin (PRL) is a secreted neuroendocrine pituitary hormone that acts primarily on the mammary gland to promote lactation; but has pleiotropic effects in both males and females. Non-glycosylated Prolactin is produced by the pituitary and packaged in storage granules before secretion; while glycosylated Prolactin is reported to be constitutively secreted; have lower biological potency; and be removed from the circulation more quickly. Prolactin is synthesized mainly by the anterior pituitary in all mammals; where secretion is under tonic inhibition by hypothalamic dopamine. In humans; Prolactin is also produced peripherally. Prolactin expression is low during early human pregnancy; but increases in late pregnancy. The Prolactin receptor (PRLR) is a transmembrane type I glycoprotein that belongs to the cytokine hematopoietic receptor family. Prolactin molecule is thought to bind two receptor molecules. In addition to its lactogenic activity; peripherally produced Prolactin plays roles in breast and prostate cancer development; regulation of reproductive function; and immunoregulation.
MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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