Name: Human PRG2/BMPG Recombinant Protein (His Tag)
Synonyms: Bone Marrow Proteoglycan;BMPG;Proteoglycan 2;Eosinophil Granule Major Basic Protein;EMBP;MBP;Pregnancy-Associated Major Basic Protein;PRG2;MBP
Expression host: HEK293 Cells
Sequence: Leu17-Tyr222
Accesstion: AAH05929.1
Species: Human
Mol_Mass: 24.6 kDa
AP_Mol_Mass: 33 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Reconstitution: Not Applicable
Background: Bone Marrow Proteoglycan (BMPG) is a secreted protein that contains one C-type lectin domain. BMPG is the predominant constituent of the crystalline core of the eosinophil granule. BMPG is highly expressed in placenta and pregnancy serum. BMPG may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin. BMPG induces non-cytolytic histamine release from human basophils. In addition, BMPG also participated in antiparasitic defense mechanisms and immune hypersensitivity reactions.
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