Name: Human PPT1 Recombinant Protein (His Tag)
Synonyms: Palmitoyl-protein thioesterase 1;PPT-1;Palmitoyl-protein hydrolase 1;PPT1
Expression host: HEK293 Cells
Sequence: Asp28-Gly306
Accesstion: P50897
Species: Human
Mol_Mass: 32.3 kDa
AP_Mol_Mass: 34-41 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5.
Reconstitution: Not Applicable
Background: Palmitoyl-protein thioesterase 1(PPT-1 for short), also known as Palmitoyl-protein hydrolase 1, belongs to the palmitoyl-protein thioesterase family. It is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. This enzyme removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Defects in PPT1 are the cause of neuronal ceroid lipofuscinosis type 1.
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