Name: Human PPP1CC Recombinant Protein (His Tag)
Synonyms: Serine/Threonine-Protein Phosphatase PP1-Gamma Catalytic Subunit;PP-1G;Protein Phosphatase 1C Catalytic Subunit;PPP1CC
Expression host: E.coli
Sequence: Met 1-Lys323
Accesstion: P36873
Species: Human
Mol_Mass: 40.2 kDa
AP_Mol_Mass: 30-40 kDa
Tag: N-His & C-His
Purity: > 85 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM DTT, pH 8.0.
Reconstitution: Not Applicable
Background: Serine/Threonine-Protein Phosphatase PP1-Υ Catalytic Subunit (PPP1CC) is a member of the PPP Phosphatase family. It is essential for cell division, participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. PPP1CC colocalizes with SPZ1 in the nucleus, with URI1 at mitochondrion, Rapidly exchanges between the nucleolar, nucleoplasmic and cytoplasmic compartments. As a cofactor, PPP1CC binds one iron ion and one manganese ion per subunit.. In addition, PPP1CC may play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II.
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