Name: Human PPIase/PPIL1 Recombinant Protein (His Tag)
Synonyms: Peptidyl-Prolyl Cis-Trans Isomerase-Like 1;PPIase;Rotamase PPIL1;PPIL1;CYPL1
Expression host: E.coli
Sequence: Met 1-Gly166
Accesstion: Q9Y3C6
Species: Human
Mol_Mass: 20.4 kDa
AP_Mol_Mass: 19 kDa
Tag: N-His
Purity: > 90 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.0.
Reconstitution: Not Applicable
Background: Peptidyl-Prolyl Cis-Trans Isomerase-Like 1 (PPIase) belongs to the cyclophilin-type PPIase family. PPIases can accelerate the folding of proteins and catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIase is a ubiquitous protein and has highly expression in heart ;skeletal and muscle. PPIase contains a PPIase cyclophilin-type domain and four Cyclosporin A binding regions. PPIase might play an important role in proliferation of cancer cells through modulation of phosphorylation of stathmin. It is suggested that PPIase can act as as a novel molecular target for colon-cancer therapy.
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