Name: Human PPIase/FKBP7 Recombinant Protein (aa 24-222, His Tag)
Synonyms: Peptidyl-Prolyl Cis-Trans Isomerase FKBP7;PPIase FKBP7;23 kDa FK506-Binding Protein;23 kDa FKBP;FKBP-23;FK506-Binding Protein 7;FKBP-7;Rotamase;FKBP7;FKBP23
Expression host: HEK293 Cells
Sequence: Gln24-Leu222
Accesstion: Q9Y680
Species: Human
Mol_Mass: 23.9 kDa
AP_Mol_Mass: 25-32 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM CaCl2, 10% Glycerol, pH 7.5.
Reconstitution: Not Applicable
Background: Peptidyl-Prolyl Cis-Trans Isomerase FKBP7 (FKBP7) is a member of the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. FKBP7 contains two EF-hand domains and one PPIase FKBP-type domain. FKBP7 exhibits PPIase activity and function as molecular chaperones. In addition, FKBP7 accelerates the folding of proteins during protein synthesis. It has been shown that Hsp90 complex to the nucleus bind its PPIase domain to cytoplasmic dynein, the motor protein responsible for retrograde movement along microtubules.
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