Name: Human Annexin A2/ANXA2 Recombinant Protein

Synonyms: Annexin A2;Annexin II;Annexin-2;Calpactin I Heavy Chain;Calpactin-1 Heavy Chain;Chromobindin-8;Lipocortin II;Placental Anticoagulant Protein IV;PAP-IV;Protein I;p36;ANXA2;ANX2;ANX2L4;CAL1H;LPC2D

Expression host: E.coli

Sequence: Ser2-Asp339

Accesstion: P07355

Species: Human

Mol_Mass: 38.6 kDa

AP_Mol_Mass: 35 kDa

Tag: None

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin:

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Histidine-HCl, 6% Sucrose, 4% Mannitol, 0.05%Tween 80, pH 5.5.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specifi

Reconstitution: Please refer to the printed manual for detailed information.

Background: Annexin A2 (ANXA2) is a member of the annexin family and has roles in the regulation of cellular growth and in signal transduction pathways. ANXA2 protein is associated with sickle cell osteonecrosis and the expression reduce of ANXA2 is associated with osteosarcoma metastases. ANXA2 functions as an autocrine factor, it can increases osteoclast formation and bone resorption. ANXA2 is involved in muscular dystrophies. In humans, the up-regulation of ANXA2 is related with colon adenocarcinoma cell differentiation.

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