Name: Human PKIB/PKI-β Recombinant Protein (His Tag)

Synonyms: cAMP-Dependent Protein Kinase Inhibitor Beta;PKI-beta;PKIB;PRKACN2

Expression host: E.coli

Sequence: Met 1-Lys78

Accesstion: Q9C010

Species: Human

Mol_Mass: 10.6 kDa

AP_Mol_Mass: 16 kDa

Tag: N-His

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin:

Storage: Store at

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 1mM DTT, 20% Glycerol, pH 8.0.

Reconstitution: Not Applicable

Background: cAMP-Dependent Protein Kinase Inhibitor β (PKI-β) is a member of the PKI family. As a member of the cAMP-dependent protein kinase inhibitor family,It has been shown that PKI-β is an extremely potent competitive inhibitor of cAMP-dependent protein kinase activity; this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. It may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer.

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