Name: Human PFKFB1 Recombinant Protein (His Tag)
Synonyms: 6-phosphofructo-2-kinase/fructose-2;6-bisphosphatase 1;6PF-2-K/Fru-2;6-P2ase liver isozyme;Fructose-2;6-bisphosphatase;PFKFB1;F6PK;PFRX
Expression host: HEK293 Cells
Sequence: Ser2-Tyr471
Accesstion: P16118
Species: Human
Mol_Mass: 55.6 kDa
AP_Mol_Mass: 60 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5% Trehalose, 1mM EDTA, pH 7.8.
Reconstitution: Not Applicable
Background: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. It belongs to the phosphoglycerate mutase family. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
Ninjurin-1 Protein
Glypican-1/GPC1 Protein
Popular categories:
Siglec-17
ADAMTS8