Name: Human Peroxiredoxin-4/PRDX4 Recombinant Protein (His Tag)
Synonyms: Peroxiredoxin-4;Antioxidant Enzyme AOE372;AOE37-2;Peroxiredoxin IV;Prx-IV;Thioredoxin Peroxidase AO372;Thioredoxin-Dependent Peroxide Reductase A0372;PRDX4
Expression host: E.coli
Sequence: Trp38-Asn271
Accesstion: Q13162
Species: Human
Mol_Mass: 28.9 kDa
AP_Mol_Mass: 30 kDa
Tag: N-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution: Not Applicable
Background: Peroxiredoxin-4 (PRDX4) is a member of the AhpC/TSA family. PRDX4 is a cytoplasmic protein and contains one thioredoxin domain. PRDX4 exists in homodimer or heterodimer with PRDX1. PRDX4 reduces hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. In addition, PRDX4 is probably involved in redox regulation of the cell, regulating the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.
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