Name: Human Parvulin-14/PIN4 Recombinant Protein (His Tag)
Synonyms: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4;Parvulin-14;Parvulin-17;Peptidyl-prolyl cis-trans isomerase Pin4;Peptidyl-prolyl cis/trans isomerase EPVH;Rotamase Pin4;PIN4;
Expression host: E.coli
Sequence: Met 1-Lys156
Accesstion: Q9Y237-2
Species: Human
Mol_Mass: 18.8 kDa
AP_Mol_Mass: 21 kDa
Tag: N-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of PBS, pH7.5.
Reconstitution: Not Applicable
Background: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4(PIN4) is a peptidyl-prolyl cis/trans isomerase (PPIase) which interacts with NIMA and is vital for cell cycle regulation. PIN4 has 2 different isoforms: PAR14 and PAR17. Furthermore, PIN4 protein binds to double-stranded DNA under physiological salt conditions. PIN4 is involved as a ribosomal RNA processing factor in ribosome biogenesis. The PAR14 binds to tightly bent AT-rich stretches of double-stranded DNA, but PAR17 binds to double-stranded DNA.
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