Name: Human NOL3 Recombinant Protein (GST Tag)
Synonyms: Nucleolar Protein 3;Apoptosis Repressor With CARD;Muscle-Enriched Cytoplasmic Protein;Myp;Nucleolar Protein of 30 kDa;Nop30;NOL3;ARC;NOP
Expression host: E.coli
Sequence: Met 1-Ser208
Accesstion: O60936
Species: Human
Mol_Mass: 48.9 kDa
AP_Mol_Mass: 30-59 kDa
Tag: N-GST
Purity: > 85 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 350mM NaCl, 1mM DTT, pH 8.0.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in
Reconstitution: Please refer to the printed manual for detailed information.
Background: Nucleolar Protein 3 is encoded by NOL3 gene; multiple transcript variants encoding different isoforms have been found for this gene. So far; Nucleolar protein 3 has show to have two Isoforms. Isoform 1 may be involved in RNA splicing.Isoform 2 may inhibit apoptosis.It has been shown to down-regulate the enzyme activities of caspase 2; caspase 8 and tumor protein p53.
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