Name: Human NDRG1 Recombinant Protein (His Tag)
Synonyms: Protein NDRG1;Differentiation-Related Gene 1 Protein;DRG-1;N-myc Downstream-Regulated Gene 1 Protein;Nickel-Specific Induction Protein Cap43;Reducing Agents and Tunicamycin-Responsive Protein;RTP;Rit42;NDRG1;CAP43;DRG1;RTP
Expression host: E.coli
Sequence: Met 1-Cys394
Accesstion: Q92597
Species: Human
Mol_Mass: 45.0 kDa
AP_Mol_Mass: 52 kDa
Tag: N-His
Purity: > 90 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Protein NDRG1 is a member of the N-Myc Downregulated Gene family, which is part of the α/β Hydrolase superfamily. Protein NDRG1 is a cytoplasmic protein that is involved in stress responses, hormone responses, cell growth and differentiation. Protein NDRG1 is necessary for p53-mediated caspase activation and apoptosis. Protein NDRG1 mutuations are reported to be the cause for hereditary motor and sensory neuropathy-Lom. Decreased NDRG1 expression in glioma is linked to tumor progression; overexpression of NDRG1 is connected to malignant status of esophageal cancer.
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