Name: Human NANS/SAS Recombinant Protein (His Tag)
Synonyms: Sialic Acid Synthase;N-Acetylneuraminate Synthase;N-Acetylneuraminate-9-Phosphate Synthase;N-Acetylneuraminic Acid Phosphate Synthase;N-Acetylneuraminic Acid Synthase;NANS;SAS
Expression host: E.coli
Sequence: Met 1-Ser359
Accesstion: AAH19315.1
Species: Human
Mol_Mass: 42.4 kDa
AP_Mol_Mass: 42 kDa
Tag: N-His
Purity: > 80 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, pH 8.0.
Reconstitution: Not Applicable
Background: Sialic Acid Synthase (NANS) is an enzyme that contains one AFP-like domain. NANS is ubiquitous and plays a role in the biosynthetic pathways of sialic acids. NANS produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN). It also can use N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively.
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