Name: Human MINPP1 Recombinant Protein (His Tag)
Synonyms: Multiple Inositol Polyphosphate Phosphatase 1;2,3-Bisphosphoglycerate 3-Phosphatase;2,3-BPG Phosphatase;Inositol (1,3,4,5)-Tetrakisphosphate 3-Phosphatase;Ins(1,3,4,5)P(4) 3-Phosphatase;MINPP1;MIPP
Expression host: HEK293 Cells
Sequence: Ser31-Leu487
Accesstion: Q9UNW1
Species: Human
Mol_Mass: 53.1 kDa
AP_Mol_Mass: 56 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5.
Reconstitution: Not Applicable
Background: Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 amino acid precursor that contains an 30 amino acid signal peptide and a 457 amino aicd mature chain. MINPP1 is widely expressed with the highest levels found in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-Phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). MINPP1 may play a role in bone development (endochondral ossification).
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