Name: Cynomolgus 5′-Nucleotidase/CD73/NT5E Recombinant Protein (His Tag)
Synonyms: 5′-Nucleotidase;5′-NT;Ecto-5′-Nucleotidase;CD73;NT5E;NT5;NTE
Expression host: HEK293 Cells
Sequence: Trp27-Lys547
Accesstion: G7P3J1
Species: Cynomolgus macaques
Mol_Mass: 58.8 kDa
AP_Mol_Mass: 58-80 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 120mM NaCl, 4mM CaCl2, 20% Glycerol, pH 7.5.
Reconstitution: Not Applicable
Background: CD73, also known as Ecto-5′-nucleotidase, is an ectoenzyme that is attached to the cell membrane by a glycosyl phophatidylinositol anchor. The enzyme is expressed by most cell types. The 5’-Nucleotidase activity of CD73 converts extracellular nucleoside-5’-monophosphates to nucleosides. CD73 is one of several enzymes responsible for the production of extracellular adenosine, a signaling molecule that is involved in responses to inflammation and tissue injury. CD73 hydrolyzes extracellular nucleotides into membrane permeable nucleosides.
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