Name: Human MAA/GSTZ1 Recombinant Protein (His Tag)
Synonyms: Maleylacetoacetate Isomerase;MAAI;GSTZ1-1;Glutathione S-Transferase Zeta 1;GSTZ1
Expression host: E.coli
Sequence: Met 1-Ala216
Accesstion: O43708
Species: Human
Mol_Mass: 25.2 kDa
AP_Mol_Mass: 25-30 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, 1mM DTT, pH 8.0.
Reconstitution: Not Applicable
Background: Maleylacetoacetate Isomerase (MAAI) belongs to the Glutathione S-Transferase super-family. MAAI encodes multifunctional enzymes in the detoxification of electrophilic molecules by conjugation with glutathione, for example, mutagens, carcinogens and several therapeutic drugs. MAAI is a bifunctional protein with low glutathione peroxidase activity with T-butyl and cumene hydroperoxides. MAAI can catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid. But it has minimal glutathione-conjugating activity with 7-chloro-4-nitrobenz-2-oxa-1, ethacrynic acid 3-diazole and maleylacetoacetate isomerase activity.
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