Name: Human LTA4H Recombinant Protein (His Tag)

Synonyms: Leukotriene A-4 hydrolase;LTA-4 hydrolase;Leukotriene A(4) hydrolase;LTA4;LTA4H

Expression host: HEK293 Cells

Sequence: Met 1-Asp611

Accesstion: P09960

Species: Human

Mol_Mass: 70.3 kDa

AP_Mol_Mass: 60-70 kDa

Tag: C-His

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin:

Storage: Store at

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at

Formulation: Supplied as a 0.2 μm filtered solution of 20mM MES, 2mM EDTA, 20% Glycerol, pH 5.0.

Reconstitution: Not Applicable

Background: LTA4H, which is short for Leukotriene A-4 hydrolase, is a 611 aa. protein. It belongs to the peptidase M1 family, and exists in cytoplasm. This protein has at least 4 isforms produced by alternative splicing, and two of them are expressed in monocytes, lymphocytes, neutrophils, reticulocytes, platelets and fibroblasts. LTA4H involves in lipid metabolism and leukotriene B4 biosynthesis. It is a epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. It also has aminopeptidase activity

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