Name: Human LMIR2/CD300C Recombinant Protein (His Tag)
Synonyms: CMRF35-Like Molecule 6;CLM-6;CD300 Antigen-Like Family Member C;CMRF35-A1;CMRF-35;Immunoglobulin Superfamily Member 16;IgSF16;CD300c;CD300C;CMRF35;CMRF35A;CMRF35A1;IGSF16
Expression host: HEK293 Cells
Sequence: Gly21-Arg183
Accesstion: Q08708
Species: Human
Mol_Mass: 18.9 kDa
AP_Mol_Mass: 40 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.Normally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.Please refer to the specific buffer information in the printed man
Reconstitution: Please refer to the printed manual for detailed information.
Background: CD300C is a single-pass type I membrane protein which belongs to the immunoregulatory signaling (IRS) family. CD300C contains one Ig-like V-type domain and is present on the surface of natural killer cells; granulocytes; most myeloid cells; dendritic cells; and a subpopulation of T and B lymphocytes. The CD300C (CMRF-35A) and CD300A (CMRF-35H) molecules are homologous leukocyte surface proteins. CD300a and CD300C play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs. CD300A and CD300C are indistinguishable on the surface of NK cells. The ligand for CD300C is presently unknown.
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