Name: Human ALDH1A3 Recombinant Protein (His Tag)
Synonyms: Aldehyde dehydrogenase family 1 member A3;ALDH1A3;Aldehyde dehydrogenase 6;Retinaldehyde dehydrogenase 3;RALDH-3;ALDH6;ALDH1A6;MCOP8;RALDH3
Expression host: E.coli
Sequence: Met1-Pro512
Accesstion: P47895
Species: Human
Mol_Mass: 57.5 kDa
AP_Mol_Mass: 55-60 kDa
Tag: N-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 20% Glycerol, pH 7.5.
Reconstitution: Not Applicable
Background: Aldehyde dehydrogenase 1 family member A3 (ALDH1A3), also known as retinaldehyde dehydrogenase 3 (RALDH3), is a member of the aldehyde dehydrogenase family known to metabolize a wide variety of aldehydes. ALDH1A3 specifically oxidizes retinal to retinoic acid (RA) and is differentially expressed in developing embryonic tissues and adult organs. The RA produced by ALDH1A3 in rodents contributes to the development of skin and hair follicles, brain, tooth buds, lungs, olfactory bulbs, kidneys, eyes, skeletal muscle and seminal vesicles. In recent research, ALDH1A3 could be as a marker of cancer stem cell to predict metastasis or clinical prognosis in many cancers.
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