Name: Human LAMTOR3/MP1 Recombinant Protein (His Tag)
Synonyms: Ragulator Complex Protein LAMTOR3;Late Endosomal/Lysosomal Adaptor and MAPK and MTOR Activator 3;MEK-Binding Partner 1;Mp1;Mitogen-Activated Protein Kinase Kinase 1-Interacting Protein 1;Mitogen-Activated Protein Kinase Scaffold Protein 1;LAMTOR3;MAP2K1IP1;MAPKSP1
Expression host: E.coli
Sequence: Met 1-Val124
Accesstion: Q9UHA4
Species: Human
Mol_Mass: 15.8 kDa
AP_Mol_Mass: 15 kDa
Tag: N-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 5mM DTT, 30% Glycerol, pH 8.0.
Reconstitution: Not Applicable
Background: Mitogen-Activated Protein Kinase Scaffold Protein 1 (MAPKSP1) was identified as an interacting protein that belongs to the LAMTOR3 family. MAPKSP1 restricted to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. MAPKSP1 interacts with MAP2K1/MEK1 and MAPK2 and enhances the activation of MAPK2, and thus is thought to function as an adaptor to enhance the efficiency of the MAP kinase cascade.
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