Name: Human KLK-8/Kallikrein-8 Recombinant Protein (His Tag)
Synonyms: Kallikrein-8;hK8;Neuropsin;NP;Ovasin;Serine Protease 19;Serine Protease TADG-14;Tumor-Associated Differentially Expressed Gene 14 Protein;KLK8;NRPN;PRSS19;TADG14
Expression host: HEK293 Cells
Sequence: Gln29-GLy260
Accesstion: AAH40887.1
Species: Human
Mol_Mass: 26.0 kDa
AP_Mol_Mass: 35 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Reconstitution: Not Applicable
Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
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