Name: Human AKR1C4 Recombinant Protein (His Tag)
Synonyms: Aldo-Keto Reductase Family 1 Member C4;3-Alpha-HSD1;3-Alpha-Hydroxysteroid Dehydrogenase Type I;Chlordecone Reductase;CDR;Dihydrodiol Dehydrogenase 4;DD-4;DD4;HAKRA;AKR1C4;CHDR
Expression host: E.coli
Sequence: Met 1-Tyr323
Accesstion: P17516
Species: Human
Mol_Mass: 39.3 kDa
AP_Mol_Mass: 35-40 kDa
Tag: N-His
Purity: > 90 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Reconstitution: Not Applicable
Background: Aldo-Keto Reductase 1C4/AKR1C4 is a member of the aldo/keto reductase family that consists of more than 40 known enzymes and proteins. AKR1C4 has highly expressed in Liver. It can catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. AKR1C4 catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-α-Androstan-3-α,17-β-diol (3-α-diol). In addition, AKR1C4 also has some 20-α-Hydroxysteroid Dehydrogenase activity.
MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
BAFFR/TNFRSF13C Protein
JAK1 Protein
Popular categories:
BTN3A1/CD277
ALK-4/Activin RIB