Name: Human Kallikrein 1/KLK1 Recombinant Protein (His Tag)
Synonyms: Kallikrein-1;Kidney/Pancreas/Salivary Gland Kallikrein;Tissue Kallikrein;KLK1
Expression host: HEK293 Cells
Sequence: Pro19-Ser262
Accesstion: AAH05313.1
Species: Human
Mol_Mass: 28.2 kDa
AP_Mol_Mass: 38-55 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 2mM CaCl2, pH 8.0.
Reconstitution: Not Applicable
Background: Kallikrein-1 (KLK1) is a member of human tissue Kallikrein family. Human KLK1 precursor contains a singal peptide (residues 1 to 18), a short pro peptide (residues 19 to 24) and a mature chain (residues 25 to 262). The function of KLK1 is to cleave Kininogen in order to release the vasoactive Kinin peptide (Lysyl-Bradykinin or Bradykinin). The Kinin peptide controls blood pressure reduction, vasodilation, smooth muscle relaxation and contraction, pain induction and inflammation. KLK1 also plays a role in angiogensis and tumorigenesis.
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