Name: Human IL-20RB Recombinant Protein (Fc Tag)
Synonyms: Interleukin-20 receptor subunit beta;IL-20 receptor subunit beta;IL-20R-beta;IL-20RB;IL-20R2;DIRS1;hCG_2022374;FNDC6;MGC34923;fibronectin type III domain containing 6;interleukin-20 receptor II
Expression host: HEK293 Cells
Sequence: Asp30-Ala230
Accesstion: Q6UXL0
Species: Human
Mol_Mass: 49.6 kDa
AP_Mol_Mass: 60-85 kDa
Tag: C-Fc
Purity: > 90 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Reconstitution: Not Applicable
Background: Interleukin-20 receptor subunit beta（IL20RB） is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family
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