Name: Human GPD1/GDP-C Recombinant Protein (Human Cells, His Tag)
Synonyms: Glycerol-3-Phosphate Dehydrogenase [NAD(+)] Cytoplasmic;GPD-C;GPDH-C;GPD1;HTGTI
Expression host: HEK293 Cells
Sequence: Met 1-Met349
Accesstion: P21695
Species: Human
Mol_Mass: 38.6 kDa
AP_Mol_Mass: 32-48 kDa
Tag: C-His
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin:
Storage: Store at
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Glycerol, pH 8.0.
Reconstitution: Not Applicable
Background: Glycerol-3-Phosphate Dehydrogenase [NAD(+)]; Cytoplasmic (GPDH-C) belongs to the NAD-Dependent Glycerol-3-Phosphate Dehydrogenase family. GPDH-C plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of Dihydroxyacetone Phosphate (DHAP) and reducing Nicotine Adenine Dinucleotide (NADH) to Glycerol-3-Phosphate (G3P) and NAD+. GPDH-C is inhibited by zinc ions and sulfate. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. GPDH-C is unlike Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH); they have different substrates.
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