Oke animals that received apelin-13 treatment had considerably greater recovery of nearby blood flow compared with all the BMP-8a Proteins Purity & Documentation stroke handle animals (77.two 3.5 vs. 85.9 0.27 in stroke car and stroke apelin-13 groups, respectively; p .05; n 10 each and every group; Figure 5(a) and (b)).ASN NeuroFigure four. Apelin-13 enhanced the long-term angiogenesis following stroke. (a) The angiogenesis in peri-infarct region was examined employing collagen IV (green) and BrdU (red) costaining at 21 days immediately after stroke. (b) Apelin-13 therapy