Targets：Enolase inhibitors
medchemexpress products name :Ziprasidone HCl hydrate BAY 41-2272
Product alias :SYN-3019
Description: Ziprasidone is a antipsychotic drug used for the treatment of schizophrenia, acute mania, and mixed states associated with bipolar disorder. Ziprassidone is a potent drug with mostly submicromolar IC50 values for principal targets. In inhibition tests, Ziprasidone is a 5HT1A/5HT2A antagonist with Ki values from 0.6 for 5HT2A, 2.3 nM for 5HT1d, but also has reasonably low Ki values for Dopamine D1-D5 receptors (Ki 7-152 nM) and other receptors like alpha 1A adrenergic receptors (Ki 18nM), Histamine 1 receptor (Ki 63 nm), and 5-HT transporter (Ki 53 n).
cas no. : 138982-67-9
Api wt. : 412.94References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/17484288