Targets:ATP Citrate Lyase inhibitors
medchemexpress products name :PF4618433 Veliparib (dihydrochloride)
Product alias :SYN-1163
Description: PF-4618433 shows improved PYK2 potency, reduced p38 activity, and superior overall selectivity relative to the prototype BIRB796. In the functional osteogenesis assays, cultures treated with increasing concentrations of PF-4618433 starting at day 1 and maintained throughout showed a dose-dependent increases in both alkaline phosphatase activity and mineralization.
cas no. : 1166393-85-6
Api wt. : 445.52References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/17483457