Targets:p97 inhibitors
medchemexpress products name :CCG-1423 Pacritinib
Product alias :SYN-5014
Description: CCG-1423 is a selective inhibitor of Rho pathway-mediated signaling and activation of serum response factor (SRF) transcription. The exact site of inhibition in the pathway in not currently known, but CCG-1423 inhibits SRF-driven luciferase expression in PC-3 cells following stimulation with constitutively active Gα13 (IC50 = 1 µM).
cas no. : 285986-88-1
Api wt. : 454.75References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/17475916